Beta-cyclodextrinhas been the most studied of thecyclodextrins. Results from numerous investigations have demonstrated its safety and metabolism.Table 22.4shows the results ofacute toxicitystudies from various routes of administration. At the maximum dose of β-cyclodextrin presented orally, no mortality related to it wasobserved. Injection of β-cyclodextrin did result in the death of animals, because it crystallized in the kidneys and caused renal damage.47Beta-cyclodextrinhas been the most studied of thecyclodextrins. Results from numerous investigations have demonstrated its safety and metabolism.Table 22.4shows the results ofacute toxicitystudies from various routes of administration. At the maximum dose of β-cyclodextrin presented orally, no mortality related to it wasobserved. Injection of β-cyclodextrin did result in the death of animals, because it crystallized in the kidneys and caused renal damage.47Beta-cyclodextrinhas been the most studied of thecyclodextrins. Results from numerous investigations have demonstrated its safety and metabolism.Table 22.4shows the results ofacute toxicitystudies from various routes of administration. At the maximum dose of β-cyclodextrin presented orally, no mortality related to it wasobserved. Injection of β-cyclodextrin did result in the death of animals, because it crystallized in the kidneys and caused renal damage.47