Excellent 2-Hydroxy with High Quality

• CAS No.: 582-17-2
• Color: White
• Appearance: Powder
• Transport Package: Paper
• Specification: large
• Trademark: china
• Origin: China
• HS Code: 2801100000
• Production Capacity: 5000kg/Year

Product Description

2-Hydroxyhydrazone based probe HNP demonstrated high selectivity towards sensing of Cu²⁺ and Al³⁺ in colorimetric and fluorimetric methods respectively. HNP can be used as "naked-eye" sensor based on the change of its color from very light yellow to bright yellow (for Cu²⁺) and colorless (for Al³⁺). The colorimetric detection mechanism for Cu²⁺ involved enhancement in internal charge transfer (ICT). In the detection of Al³⁺ through fluorescence, combined effect of ICT and excited-state intramolecular proton transfer (ESIPT) played major role. Job's plots based on UV-vis (Cu²⁺) and fluorescence (Al³⁺) data along with mass spectral study indicated 1:1 metal to HNP stoichiometry. The binding of the probe HNP with Al³⁺ and Cu²⁺ was found chemically reversible on addition of EDTA. Binding mode of the probe with the metal ions was proposed based on spectroscopic data and density functional theory (DFT). Moreover, effect of pH and response time was also determined. The probe was found useful for in vivo detection and imaging of Al³⁺ in MDA-MB-231 cells. Paper strips of the probe were made and used for naked eye detection of Cu²⁺ and Al³⁺. The probe was also used in the construction of logic gate for detection of Al³⁺.