CAS No.: | 578-86-9 |
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Color: | White |
Appearance: | Powder |
Transport Package: | Paper |
Specification: | large |
Trademark: | china |
Samples: |
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Pepsin, the powerful enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, or dairy products. Pepsin is the mature active form of the zymogen (inactive protein) pepsinogen.
Pepsin was first recognized in 1836 by the German physiologist Theodor Schwann. In 1929 its crystallization and protein nature were reported by American biochemist John Howard Northrop of the Rockefeller Institute for Medical Research. (Northrop later received a share of the 1946 Nobel Prize for Chemistry for his work in successfully purifying and crystallizing enzymes.)
Glands in the mucous-membrane lining of the stomach make and store pepsinogen. Impulses from the vagus nerve and the hormonal secretions of gastrin and secretin stimulate the release of pepsinogen into the stomach, where it is mixed with and rapidly converted to the active enzyme pepsin. The digestive power of pepsin is greatest at the acidity of normal gastric juice (pH 1.5-2.5). In the intestine the gastric acids are neutralized (pH 7), and pepsin is no longer effective.
Pepsin, the powerful enzyme in gastric juice that digests proteins such as those in meat, eggs, seeds, or dairy products. Pepsin is the mature active form of the zymogen (inactive protein) pepsinogen.
Pepsin was first recognized in 1836 by the German physiologist Theodor Schwann. In 1929 its crystallization and protein nature were reported by American biochemist John Howard Northrop of the Rockefeller Institute for Medical Research. (Northrop later received a share of the 1946 Nobel Prize for Chemistry for his work in successfully purifying and crystallizing enzymes.)
Glands in the mucous-membrane lining of the stomach make and store pepsinogen. Impulses from the vagus nerve and the hormonal secretions of gastrin and secretin stimulate the release of pepsinogen into the stomach, where it is mixed with and rapidly converted to the active enzyme pepsin. The digestive power of pepsin is greatest at the acidity of normal gastric juice (pH 1.5-2.5). In the intestine the gastric acids are neutralized (pH 7), and pepsin is no longer effective.
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