Excellent Microcrystalline Cellulose with High Quality

• CAS No.: 7320-34-5
• Color: White
• Appearance: Powder
• Transport Package: Paper
• Specification: large
• Trademark: china
• Model NO.: E1422
• Origin: China
• HS Code: 2930400000
• Production Capacity: 5000kg/Year

Product Description

Microcrystalline cellulose (MCC) is the most commonly used spheronizing aid in a formulation undergoing extrusion spheronization. It is available in different grades and particle sizes. Of all the different brands and grades of MCC, Avicel PH 101 or Emcocel 50 has been the most widely used. MCC helps in the formation of spheres because of its unique properties. Like other cellulosic materials, MCC is a filamentous material with a large surface area, high internal porosity, and high moisture retaining property (Shah et al., 1995).

MCC is the golden standard as an extrusion spheronization aid based on its good binding properties that provide cohesiveness to a wetted mass containing MCC. Furthermore, it is able to absorb and retain a large quantity of water due to its large surface area and high internal porosity (Sonaglio et al., 1995), thus facilitating extrusion, improving wetted mass plasticity and enhancing spheronization. Moreover, by controlling the movement of water through the plastic mass, it prevents phase separation during extrusion or spheronization. Due to these properties MCC-based pellets produced via extrusion spheronization have a good sphericity, low friability, high density, and smooth surface properties.

Its capacity to retain very large quantities of water internally means that wet masses made with MCCs have rheological properties that are very suitable for extrusion spheronization (Fielden et al., 1992a, 1995).