Gellan gumis a water-soluble anionicexopolysaccharideproduced by bacteria from theSphingomonasgroup. The gellan gum has been broadly used in biomedical applications since the FDA approval in 1992 for its biocompatibility and low cytotoxicity. The gellan gum chains can interlock with each other and form a coherent network that entraps a very high (∼99%) volume fraction of water. Similar to alginate, the junction zones of gellan gum networks could be crosslinked by multivalent cations, commonly Ca2+or Mg2+, and form a hydrogel at low temperatures. There have been many studies using gellan gum mixed with other biomaterials as a bioink forboneand cartilage bioprinting (Akkineni et al., 2016;Mouser et al., 2016). A recent study synthesized gellan gum and PLGA into copolymers as the bioink for cartilage bioprinting Gellan gumis a water-soluble anionicexopolysaccharideproduced by bacteria from theSphingomonasgroup. The gellan gum has been broadly used in biomedical applications since the FDA approval in 1992 for its biocompatibility and low cytotoxicity. The gellan gum chains can interlock with each other and form a coherent network that entraps a very high (∼99%) volume fraction of water. Similar to alginate, the junction zones of gellan gum networks could be crosslinked by multivalent cations, commonly Ca2+or Mg2+, and form a hydrogel at low temperatures. There have been many studies using gellan gum mixed with other biomaterials as a bioink forboneand cartilage bioprinting (Akkineni et al., 2016;Mouser et al., 2016). A recent study synthesized gellan gum and PLGA into copolymers as the bioink for cartilage bioprinting (Pitarresi et al., 2020).