Excellent Erythrosine with High Quality

• CAS No.: 568-63-8
• Color: Red
• Appearance: Liquid
• Transport Package: Paper
• Specification: large
• Trademark: china
• Model NO.: E1422
• Origin: China
• HS Code: 2930400000
• Production Capacity: 5000kg/Year

Product Description

Erythrosine (FD&C red no. 3) is one the best characterized chemicals that acts as a 5′-deiodinase inhibitor and results in perturbations of thyroid function. It is a tetraiodinated derivative of fluorescein, with iodine accounting for ~58% of the molecular weight. Erythrosine is a red dye used widely as a color additive in foods, cosmetics, and pharmaceuticals. Amiodarone is an organic iodinated antiarrhythmic compound that also disrupts thyroid hormone economy by inhibiting 5′-deiodinase. Iopanoic acid and flavonoids also inhibit the enzyme in hepatocytes.

Erythrosine alters the peripheral metabolism of T₄. Inhibition of 5′-deiodinase in the liver and kidney by erythrosine causes lower circulating T₃ levels. This results in accumulation of inactive reverse T₃. The lowered circulating levels of T₃ causes increased secretion of TSH from the pituitary and stimulation of thyroid follicular cells.

Erythrosine (FD&C red no. 3) is one the best characterized chemicals that acts as a 5′-deiodinase inhibitor and results in perturbations of thyroid function. It is a tetraiodinated derivative of fluorescein, with iodine accounting for ~58% of the molecular weight. Erythrosine is a red dye used widely as a color additive in foods, cosmetics, and pharmaceuticals. Amiodarone is an organic iodinated antiarrhythmic compound that also disrupts thyroid hormone economy by inhibiting 5′-deiodinase. Iopanoic acid and flavonoids also inhibit the enzyme in hepatocytes.

Erythrosine alters the peripheral metabolism of T₄. Inhibition of 5′-deiodinase in the liver and kidney by erythrosine causes lower circulating T₃ levels. This results in accumulation of inactive reverse T₃. The lowered circulating levels of T₃ causes increased secretion of TSH from the pituitary and stimulation of thyroid follicular cells.